Charlie is a well-to-do jingle-writing bachelor with a house at the beach in Malibu, a luxury car in the garage, and an easy way with women. His casual lifestyle is interrupted when his tightly wound chiropractor brother Alan, who’s facing a divorce, and his son Jake, come to live with him. Together, these two and a half men confront the challenges of growing up. Complicating matters are the brothers’ self-obsessed, controlling mother, Evelyn, Alan’s estranged wife, Judith, and Charlie’s crazy neighbor Rose, who wants to be a part of his life and is willing to do anything to be around.
After season 8, Charlie was killed off and replaced by a wealthy bachelor named Walden who befriends Alan, buys Charlie’s home, and lets Alan continue to live there.